Rejuran is a polynucleotide skin booster derived from salmon DNA. Instead of filling a line or relaxing a muscle, it helps your skin repair itself — improving elasticity, fine lines, hydration, and even acne scars over a series of sessions.
If you follow Korean skincare, you have probably seen Rejuran mentioned alongside glass-skin routines and clinic vlogs from Seoul. Koreans call it the "healer" injection, and it has been a mainstay of K-beauty clinics for about a decade. It is now available at Jeune Medspa in La Habra. Here is a plain-English guide to how it works and whether it fits your goals.
Key Takeaways
- Rejuran is a polynucleotide skin booster derived from salmon DNA — it repairs skin quality rather than adding volume.
- It targets elasticity, fine lines, the skin barrier, under-eye crepiness, and acne scars.
- Plan on a series of 3–4 sessions spaced 2–4 weeks apart; injection bumps settle within about 24–48 hours.
- At Jeune, Rejuran runs $350–$450 per session depending on the variant.
- It complements Botox and filler rather than replacing them — each solves a different problem.
What Rejuran is, exactly
Rejuran is an injectable treatment whose active ingredient is polynucleotides — chains of DNA fragments derived from salmon DNA. Your provider places it into the skin as a pattern of tiny microdroplet injections across the treatment area.
Rather than sitting in the skin as a volumizer, those polynucleotides act as a repair signal. Over the following weeks, treated skin tends to become more elastic, better hydrated, and smoother in texture — which is why the treatment earned its "healer" nickname in Korea. You can read more about how we approach it on our Rejuran skin booster page.
If you have searched for a "salmon DNA skin treatment" and wondered whether that is really a thing — yes, this is it. The salmon-derived polynucleotide is the entire point of the product.
Repair, not fill: how Rejuran differs from filler and Botox
This is the most common point of confusion, so it is worth spelling out. Dermal filler adds volume — it physically fills a fold, a hollow, or a lip. Neurotoxin injections like Botox relax the muscles that crease the skin when you frown or squint.
Rejuran does neither. It does not add volume, and it does not touch your muscles. It works on the quality of the skin itself — its elasticity, hydration, barrier, and texture. That is why many patients use Rejuran alongside filler or tox rather than instead of them. They solve different problems.
What Rejuran can help with
Because it works by repairing skin from within, Rejuran is best suited to concerns that come from skin quality rather than volume loss or muscle movement:
- Loss of elasticity — skin that feels thinner or less bouncy than it used to
- Fine lines, especially the crepey lines under the eyes
- A weakened skin barrier — skin that feels dry, reactive, or dull
- Acne scars, where a dedicated Rejuran Scar formulation is used
- Uneven tone, addressed by the brightening Tone-Up variant
Our clientele tends to want results that read as "your skin, but healthier" rather than an obviously worked-on look — and that is exactly the lane Rejuran occupies.
Rejuran pricing at Jeune Medspa
We carry five Rejuran formulations, each aimed at a different concern:
- Rejuran Healer (2cc) — the classic full-face anti-aging treatment: $450
- Rejuran HB — blended with hyaluronic acid for deep hydration: $350
- Rejuran Eyes — formulated for under-eye fine lines: $350
- Rejuran Scar — targeted at acne scarring: $350
- Rejuran Tone-Up — the brightening variant: $350
If you are not sure which one fits, that is a normal starting point — matching the formulation to your skin is part of what the consultation is for.
What a session — and the full series — feels like
Rejuran is not a one-and-done treatment. It is typically done as a series of 3 to 4 sessions spaced 2 to 4 weeks apart, because repair happens gradually as your skin responds between visits.
Each session involves a pattern of small, shallow microdroplet injections across the treatment area. You will leave with tiny raised bumps where the product was placed — this is normal and expected, and they settle within about 24 to 48 hours. Many patients simply plan their appointment for a day when they can keep a low profile that evening.
Because Rejuran works by repair rather than by filling, the change arrives quietly over the series — smoother texture, better bounce, a more even look — rather than as a dramatic same-day transformation.
How Rejuran compares to other skin boosters
Rejuran is one of several skin boosters we offer. If you are comparing options, start with our injectable skin booster overview and the full skin booster menu. Here is how current per-session pricing lines up:
| Skin booster | Price per session |
|---|---|
| Exosome | $700 |
| Juvelook | $650 |
| SkinVive | $600 |
| Rejuran (five variants) | $350–$450 |
| Pure HA | $250 |
| Glutathione | $250 |
| PRP | $250 |
Each booster works differently, and the right choice depends on your skin, your goals, and your budget. Rejuran's niche is repair — if your main complaint is overall skin quality, elasticity, or acne scarring, it is usually the first one we discuss.
Pairing it with RF microneedling
Rejuran pairs well with RF microneedling, which uses fine needles and radiofrequency energy to work on texture and firmness through a different mechanism. Patients dealing with acne scars or laxity may benefit from combining the two approaches.
Sequencing matters, though, so we plan combined treatments case by case rather than stacking everything into one visit. For acne scarring, for example, that might mean mapping out where your Rejuran Scar sessions and your microneedling sessions each fall on the calendar, so your skin has time to respond between appointments.
Who Rejuran is not for — honest expectations
Rejuran is a skin-quality treatment, and it is worth being clear about what that means:
- It will not replace filler or tox. Volume loss and expression lines are filler and neurotoxin territory, as covered above.
- It is not a same-day dramatic fix. If you want a visible change by the weekend, Rejuran's gradual, cumulative approach will frustrate you.
- It asks for commitment. A proper course is 3 to 4 sessions — a single session gives you a fraction of the benefit.
As with any aesthetic treatment, results vary from person to person, and an honest consultation matters more than any product name. If Rejuran is not the right tool for your concern, we will tell you and point you toward what is.
Trying Rejuran in La Habra
Jeune Medspa is a boutique med spa at 721 W. Whittier Blvd, Suite Q in La Habra — a short drive from Fullerton, Brea, and Whittier. Consultations are complimentary, and if you would like to spread out the cost of a series, we offer financing through Cherry.
Curious what results look like in real patients? Browse our before and after gallery, then book a complimentary consultation online or call (562) 332-1300. We are open Tuesday, Thursday, Friday, and Saturday from 11am to 7pm.
Frequently Asked Questions
How much does Rejuran cost at Jeune Medspa?
Four of our five Rejuran variants — HB, Eyes, Scar, and Tone-Up — are $350 per session, and the full-face Rejuran Healer 2cc is $450 per session. Most treatment plans involve a series of 3 to 4 sessions. Consultations are complimentary, and Cherry financing is available if you prefer to pay over time.
Does Rejuran hurt, and is there any downtime?
A session consists of many small, shallow microdroplet injections across the treatment area. The most noticeable after-effect is the pattern of tiny raised bumps left at the injection points, which settle within about 24 to 48 hours. Most patients simply plan the appointment for a day when they can take it easy that evening.
How many Rejuran sessions do I need, and when will I see results?
A typical course is 3 to 4 sessions spaced 2 to 4 weeks apart. Because Rejuran works by helping the skin repair itself rather than by filling, improvements build gradually across the series instead of appearing overnight. Your provider will map out a schedule for your skin at the consultation.
Is Rejuran safe? It is made from salmon DNA, after all.
Rejuran's active ingredient is polynucleotides derived from salmon DNA, and the treatment has been a fixture in Korean clinics for roughly a decade. A track record is not the same as a personal green light, though — your provider will review your health and allergy history and assess whether Rejuran suits your skin before treating you. That conversation is part of the complimentary consultation, so bring any concerns with you.
What is the difference between Rejuran and Botox or filler?
Filler adds volume to a specific area, and Botox-type injections relax the muscles that crease the skin. Rejuran does neither — it improves the quality of the skin itself, including elasticity, hydration, and texture. Many patients combine it with filler or tox because the three address different problems.
Where can I get Rejuran near me?
Jeune Medspa offers all five Rejuran formulations at 721 W. Whittier Blvd, Suite Q in La Habra, serving north Orange County. We are open Tuesday, Thursday, Friday, and Saturday from 11am to 7pm. Book a complimentary consultation online or call (562) 332-1300.
This article is for general education and is not medical advice. Individual results vary. A complimentary in-person consultation at Jeune Medspa is the best way to find out whether a treatment is right for you.