Med Spa Services · Skin Booster · Injectable

Rejuran Skin Booster

Five precision polynucleotide formulas — each engineered to repair, regenerate, and rejuvenate a specific skin concern from within.

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What Is Rejuran?

Rejuran is a revolutionary category of injectable skin booster derived from polynucleotides (PN) — long-chain DNA fragments extracted from salmon PDRN (polydeoxyribonucleotide). These biologically active molecules are remarkably compatible with human DNA and are recognized by skin cells as a signal to initiate repair, regeneration, and collagen synthesis.

Unlike hyaluronic acid skin boosters that primarily hydrate, Rejuran works at a deeper biological level: it activates fibroblasts (the cells responsible for producing collagen and elastin), promotes cellular repair, reduces inflammation, and restores skin structure from the inside out. The result is genuine biological rejuvenation — thicker, more elastic, better-hydrated skin that looks and feels fundamentally healthier.

Originating from South Korea, where it became one of the most sought-after aesthetic treatments among dermatologists and their patients, Rejuran has a robust clinical evidence base supporting its safety and efficacy. It is now available at Jeune Medspa in five specialized formulations, each targeting a distinct skin concern.

Key Benefits Across All Rejuran Formulas

Series 1 · Foundation

Rejuran Healer

The original and most versatile Rejuran formula, Rejuran Healer is ideal for first-time users or anyone seeking a comprehensive baseline skin repair treatment. Its balanced polynucleotide concentration stimulates fibroblast activity to improve skin texture, elasticity, and hydration while laying the groundwork for more advanced rejuvenation. An excellent starting point for patients new to skin boosters.

Best for: First-time Rejuran patients, general skin quality improvement, texture refinement, and collagen restoration.

Series 2 · Anti-Aging

Rejuran HB / High Balance

Rejuran HB contains a higher concentration of polynucleotides than the original Healer, delivering a more intensive collagen stimulation and anti-aging response. The "High Balance" formulation is designed for patients with more advanced signs of aging who need a stronger biological signal to restore dermal density, improve skin firmness, and reduce visible wrinkles. Often recommended as a step up from Healer or as a primary treatment for mature skin.

Best for: Moderate-to-advanced aging, deeper wrinkles, significant loss of skin density, and patients seeking accelerated results.

Series 3 · Eye Area

Rejuran Eyes (I)

Specially formulated with a lighter viscosity for the uniquely delicate periorbital zone, Rejuran Eyes targets the most visible signs of aging and fatigue around the eyes. By stimulating collagen production and improving skin thickness in this fragile area, it visibly reduces dark circles caused by skin thinning, diminishes puffiness, and lifts the appearance of sagging lower lids and crepey upper eyelid skin. A standalone treatment or powerful complement to under-eye filler.

Best for: Dark circles (especially thinning-related), under-eye hollowness, fine lines, puffiness, and upper eyelid laxity.

Series 4 · Scar Repair

Rejuran Scar

Rejuran Scar is a concentrated formulation engineered specifically for dermal reconstruction in scarred tissue. Whether from acne, surgical procedures, or injury, scars represent zones of disorganized collagen that have lost their normal architecture. Rejuran Scar delivers intensive polynucleotide stimulation to reactivate fibroblasts within and around scar tissue, promoting organized collagen deposition that gradually fills depressed scars, softens textural irregularities, and restores a smoother skin surface.

Best for: Acne scars (ice-pick, boxcar, rolling), depressed atrophic scars, post-surgical scars, and areas of dermal damage.

Series 5 · Brightening

Rejuran Tone Up

Rejuran Tone Up combines the foundational skin-repairing properties of polynucleotides with targeted brightening actives to address uneven skin tone, dullness, and hyperpigmentation. By stimulating cellular renewal and improving overall skin quality at the dermal level, it produces a brighter, more luminous complexion that goes beyond surface-level whitening. Ideal for patients whose primary concern is a lackluster or uneven skin tone that has not responded adequately to topical treatments.

Best for: Dull or sallow complexion, uneven skin tone, mild hyperpigmentation, post-inflammatory discoloration, and overall radiance improvement.

Treatment Protocol

For optimal results, we recommend a series of 3 sessions spaced approximately 4 weeks apart. Each session takes 30–45 minutes and involves multiple superficial microinjections across the treatment area. A topical numbing cream is applied beforehand for maximum comfort. Results typically become visible 2–4 weeks after the first session, with the full benefit of the series apparent at 3 months post-final treatment.

Maintenance sessions every 6–12 months sustain the improvements and provide ongoing biological anti-aging benefits.

What to Expect

After treatment, you may notice small papules (raised bumps) at injection sites that resolve within 24–48 hours. Mild redness and swelling are normal and typically resolve within a day. There is no significant downtime, and most patients resume normal activities the following day. Results build progressively and naturally over the weeks following treatment.

Aftercare

Why Rejuran at Jeune?

Five Specialized Formulas

We carry the complete Rejuran series — Healer, HB, Eyes, Scar, and Tone Up — so we can precisely match the right formula to your specific concern.

Biological Regeneration

Rejuran works at a cellular level — activating your skin's own repair mechanisms rather than simply adding a substance on top.

Clinically Proven

Backed by extensive Korean dermatological research, Rejuran has one of the strongest clinical evidence bases of any skin booster available.

Progressive Results

Unlike HA boosters, Rejuran improves over time as collagen remodeling unfolds — results genuinely get better over 3 months.

Complementary Pairing

Rejuran pairs beautifully with energy devices (HIFU, RF) and other injectables for a comprehensive multi-modal rejuvenation program.

Minimal Downtime

Most patients return to their normal routine within 24 hours. Pinpoint papules resolve within a day, leaving clear, refreshed skin.

Location

721 W. Whittier Blvd
Suite Q, La Habra, CA 90631

Hours

Tue, Thu, Fri & Sat
11:00 AM – 7:00 PM
Wednesday closed

Get in Touch

(562) 332-1300
rosemila2010@gmail.com

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